解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Connective tissue microfibrils were observed in tissues prepared with methods believed to minimize the loss of tissue components. The eyes of C57BL/6J mice were fixed with glutaraldehyde followed by either freeze substitution, or embedding in glycol methacrylate, a water-miscible embedding medium, after limited or no ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318486
更新日期:1995-02-01 00:00:00
abstract::In this study, we demonstrate the role of M cells in uptake of poly(D-L-lactic-co-glycolic acid) (PLGA) microspheres and transport into rabbit Peyer's patches. Microspheres 1 to 10 microns in diameter composed of 50:50 lactic acid:glycolic acid were instilled into intestinal segments containing jejunal or ileal Peyer'...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318501
更新日期:1995-02-01 00:00:00
abstract::Rat endometrial explants were cultured in a three-dimensional collagen/endothelial cell matrix to measure angiogenic activity, as represented by migration of vascular endothelial cells towards the explants. Minimal endothelial cell migratory activity was observed with endometrial explants taken during the four-day oes...
journal_title:Cell and tissue research
pub_type: 历史文章,杂志文章
doi:10.1007/BF00300706
更新日期:1995-01-01 00:00:00
abstract::The effects of radiotherapy on neuropeptide expression in the rat larynx were studied. Irradiation was given for five days, 6 or 8 Gray daily. Ten days after the end of irradiation, the larynx, the laryngeal nerves and different ganglia related to the larynx were dissected out from irradiated and control animals and p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00300691
更新日期:1995-01-01 00:00:00
abstract::Because leucokinins stimulate diuresis in some insects, we wished to identify the neurosecretory cells in Manduca sexta that might be a source of leucokinin-like neurohormones. Immunostaining was done at various stages of development, using an antiserum to leucokinin IV. Bilateral pairs of neurosecretory cells in abdo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00331367
更新日期:1994-12-01 00:00:00
abstract::Chorionic binucleate cells (BNC) occur in several ruminants including cow, deer, goat and sheep. They migrate through the chorionic tight junction to fuse with uterine epithelial cells and discharge their granules into maternal connective tissue. We have compared the BNC of near-term, resin-embedded, ovine and bovine ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00331380
更新日期:1994-12-01 00:00:00
abstract::Nitric oxide and various neuropeptides in the myenteric plexus regulate esophageal motility. We sought colocalization of nitric oxide synthase and neuropeptides in frozen sections of mid-portion of smooth-muscled opossum esophagus using NADPH-diaphorase activity to mark the synthase and immunoreactivity to detect pept...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00331374
更新日期:1994-12-01 00:00:00
abstract::The three-dimensional architecture of the tubular endocytic apparatus and the endoplasmic reticulum in the rat yolk-sac endoderm was investigated after loading with horseradish peroxidase-conjugated concanavalin A by intrauterine administration. After 30 min, small vesicles (50-150 nm in diameter), small tubules (80-1...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00414178
更新日期:1994-11-01 00:00:00
abstract::This study documents neuronal differentiation in vitro from undifferentiated precursor cells of caudalmost regenerating spinal cord of the teleost Apteronotus albifrons. At 11 days in vitro, cells from the caudalmost tip of the regenerating cord are flat and polygonal in shape, lack neuronal processes and do not stain...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00414166
更新日期:1994-11-01 00:00:00
abstract::In the present study, immunogold labeling of ultrathin sections of rat small intestine and liver has been used to obtain insights into the ultrastructural localization and possible functions of annexins. In enterocytes, annexins II, IV, and VI are found at the periphery of the core of each microvillus and of the rootl...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00414181
更新日期:1994-11-01 00:00:00
abstract::In the present study, we used ultrastructural cytochemistry to analyze the distribution of nuclear and cytoplasmic nucleic acids and polysaccharides, and electron spectroscopic imaging to map the element phosphorus in immature erythroid cells taken from two amphibians, the diploid Bufo ictericus and the tetraploid Odo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00305791
更新日期:1994-10-01 00:00:00
abstract::Transgenic rats for the murine Ren-2 gene display high blood pressure, low circulating levels of angiotensin II, and high renin content in the adrenal glands. Moreover, transgenic rats possess an increased aldosterone secretion (maximal from 6 to 18 weeks of age), paralleling the development of hypertension. To invest...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00305774
更新日期:1994-10-01 00:00:00
abstract::The fine structure of the main excretory duct epithelium (MEDE) of female mouse submandibular gland was investigated by scanning and transmission electron microscopy and the results compared with the previously established structure of male mouse MEDE. A comparative analysis of the subepithelial capillaries of both se...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00300213
更新日期:1994-09-01 00:00:00
abstract::Pituitary adenylate cyclase-activating polypeptide (PACAP) and helospectin are two vasoactive intestinal polypeptide (VIP)-related neuropeptides that have recently been demonstrated in the mammalian gut; the aim of this study was to reveal their occurrence and localisation in the gastrointestinal tract, swimbladder, u...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00300227
更新日期:1994-09-01 00:00:00
abstract::The enteric nervous system appears to play a pivotal role in the functional recovery of the gastrointestinal tract after partial resection and reanastomosis, but the structural changes following surgery are not fully understood. The present study was designed to clarify the processes of myenteric plexus regeneration u...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327773
更新日期:1994-08-01 00:00:00
abstract::We demonstrate the existence of nerve fibers possessing substance P (SP) and calcitonin gene-related peptide (CGRP) immunoreactivity in the mouse cervical ventral roots. The distribution of the SP and CGRP fibers was similar, but CGRP fibers were generally more numerous. Both types entered the ventral pia mater or for...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327774
更新日期:1994-08-01 00:00:00
abstract::The prothoracicotropic hormone (PTTH), which stimulates ecdysteroid synthesis in the prothoracic glands, is produced, in the dorso-lateral protocerebrum of Manduca sexta, by paired peptidergic neurons, the lateral neurosecretory cell group III (L-NSC III). Our study revealed ultrastructural features of L-NSC III, iden...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00303082
更新日期:1994-07-01 00:00:00
abstract::The distribution and abundance of nitric oxide synthase (NOS)-containing neurons and their terminals in the gastrointestinal tract of the guinea-pig were examined in detail using NADPH diaphorase histochemistry and NOS immunohistochemistry. NOS-containing cell bodies were found in the myenteric plexus throughout the g...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00303090
更新日期:1994-07-01 00:00:00
abstract::The medial preoptic nucleus of the Japanese quail is a testosterone-sensitive structure that is involved in the control of male copulatory behavior. The full understanding of the role played by this nucleus in the control of reproduction requires the identification of its afferent and efferent connections. In order to...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00343944
更新日期:1994-06-01 00:00:00
abstract::The expression of the gene for vasoactive intestinal polypeptide (VIP) and peptide histidine methionine (PHM) in the human gastrointestinal tract was studied by in situ hybridization and Northern blotting for PHM/VIP mRNA and immunocytochemistry using specific antisera against the bioactive peptides PHM and VIP. In th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00306108
更新日期:1994-05-01 00:00:00
abstract::Antibodies to smooth muscle and non-muscle myosin allow the development of smooth muscle and its capillary system in the embryonic chicken gizzard to be followed by immunofluorescent techniques. Although smooth muscle development proceeds in a serosal to luminal direction, angiogenetic cell clusters develop independen...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00306123
更新日期:1994-05-01 00:00:00
abstract::The present study describes substance P-like immunoreactivity in the ciliary ganglia of monkey (Macaca fascicularis) and cat. About 60% of neurons in the monkey ciliary ganglion and 40% in the cat ciliary ganglion were substance P-like immunoreactive, ranging from faint to moderate staining. Substance P-like immunorea...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00354796
更新日期:1994-04-01 00:00:00
abstract::Large granular lymphocytes (LGL) comprise a natural defense system in the liver and exert an inhibitory effect on tumor cell metastasis. In order to demonstrate the maturation of LGL in the liver from the morphological aspect, we evaluated electron-microscopically the frequency of 0.2 micron vesicles (rod-cored and "e...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00354799
更新日期:1994-04-01 00:00:00
abstract::The present lectin histochemical comparison of cauda epididymal and ampullary bovine sperm was conducted to investigate whether ampullary secretions are involved in altering the plasma-membrane glycoconjugates of sperm. A marked redistribution of glycoconjugates between sperm from these two regions was indeed revealed...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318822
更新日期:1994-03-01 00:00:00
abstract::The formation of secretory granules in chronically hypersecretory melanotrophs in the rat pituitary was studied. Hypersecretion was induced by treatment with the dopamine antagonist haloperidol (1.5 mg/kg daily for 7 days), which releases the normal neural dopaminergic inhibition of secretion from the melanotroph. Mor...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00319432
更新日期:1994-02-01 00:00:00
abstract::The ontogeny of protein gene product 9.5 (PGP 9.5), serotonin (5-HT), calcitonin gene-related peptide (CGRP), and calcitonin (CT) immunoreactivity was evaluated in small-granule endocrine cells of hamster laryngotracheal epithelium from fetal day 11 to adulthood. Two centrifugal (proximal-to-distal) patterns of differ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00305382
更新日期:1994-01-01 00:00:00
abstract::The distribution of VIP-like perikarya and fibers was determined throughout the chick brain. The most rostral immunoreactive perikarya were found to be cerebrospinal fluid-contacting neurons in the pars medialis of the lateral septal organ. Additional data were presented supporting the idea that the lateral septal org...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00305378
更新日期:1994-01-01 00:00:00
abstract::This is the first report on the ultrastructural pattern of distribution of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) in endothelial cells, using the rabbit aorta, and its colocalization with the neuronal isoform (type I) of nitric oxide synthase. About 30% of the endothelial cells showed a posit...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00314551
更新日期:1993-12-01 00:00:00
abstract::Placing the clawed toad Xenopus laevis on a black background stimulates the melanotrope cells in the pars intermedia of the pituitary gland to release proopiomelanocortin (POMC)-derived peptides, including alpha-MSH and N-acetyl-beta-endorphin. In this study three types of secretory granules, electron-dense (approxima...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00314557
更新日期:1993-12-01 00:00:00
abstract::The distribution of nerve fibres in the mucosa of the nasal septum of the rat was investigated by means of transmission electron microscopy on transverse and tangential ultrathin sections. Near the basement membrane of respiratory and squamous epithelium, a rather dense network of unmyelinated nerve fibres occurs. Som...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318751
更新日期:1993-11-01 00:00:00
abstract::In the present study, we characterized intra-epithelial leukocytes in the digestive tract of chickens during postnatal development. Their phenotype was characterized by monoclonal antibodies in cryostat sections and the numbers of the different cell-types were counted in the epithelium of the esophagus, proventriculus...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318748
更新日期:1993-11-01 00:00:00
abstract::To determine whether lipid-secreting cells have cytosolic Ca2+ concentration ([Ca2+]c)-related secretory mechanisms, morphological changes and intracellular calcium dynamics of Harderian glands of guinea pigs stimulated by secretagogue were studied by electron microscopy and Fura-2/AM digital image analysis. Control g...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327979
更新日期:1993-10-01 00:00:00
abstract::The immunocytochemical localization of bovine oviduct-specific glycoproteins was investigated by light and electron microscopy. Using monoclonal antibodies (MAbs) specific for bovine oviductal glycoproteins, 3 regions (fimbriae, ampulla, and isthmus) of the epithelium in the bovine oviduct we studied during the follic...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327983
更新日期:1993-10-01 00:00:00
abstract::The effect of vascular endothelial growth factor (VEGF165) on the chorioallantoic membrane (CAM) of 13-day-old chick embryos was studied. The factor was applied in doses of 0.5-4 micrograms for a period of up to 4 days. Macroscopical, histological and immunohistological studies were carried out. The localization of th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327997
更新日期:1993-10-01 00:00:00
abstract::Developmental alterations of paranodal fiber segments have not been investigated systematically in human nerve fibers at the light- and electron-microscopic level. We have therefore analyzed developmental changes in the fine structure of the paranode in 43 human sural nerves during the axonal growth period up to 5 yea...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00333704
更新日期:1993-09-01 00:00:00
abstract::The pars tuberalis of the hypophysis of the Djungarian hamster, Phodopus sungorus, was investigated with regard to secretory activity by applying the tannic acid-Ringer perfusion technique. Two groups were maintained under long photoperiods (16 h light: 8 h dark) or short photoperiods (8 h light: 16 h dark), respectiv...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00312830
更新日期:1993-08-01 00:00:00
abstract::When tissues are processed for electron microscopy by conventional methods, such as glutaraldehyde fixation followed by rapid dehydration in acetone, basement membranes show two main layers: the electron-lucent "lamina lucida". (or rara) and the electron-dense "lamina densa". In an attempt to determine whether this su...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00304610
更新日期:1993-07-01 00:00:00
abstract::The colocalization of immunoreactivities to substance P and calcitonin gene-related peptide (CGRP) in nervous structures and their correlation with other peptidergic structures were studied in the stellate ganglion of the guinea pig by the application of double-labelling immunofluorescence. Three types of fibre were d...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318563
更新日期:1993-06-01 00:00:00
abstract::The elements Na, Cl and K are distributed heterogeneously in the larval cells of the four Malpighian tubules of Drosophila hydei. Elemental gradients are steeper when they are related to the dry weight in comparison to the weight of water. The high contents of Na, Cl and K in the cytoplasm close to the basal plasma me...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318555
更新日期:1993-06-01 00:00:00
abstract::Interstitial cells in the pineal gland of the rat were characterized immunocytochemically using the monoclonal antibodies MRC OX-42 and ED1 for macrophages/microglia, and MRC OX-6, which recognizes major histocompatibility complex (MHC) class II antigen. A polyclonal antibody against GFAP was used to identify astrocyt...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00302731
更新日期:1993-05-01 00:00:00